The airstrike was carried out near an extremist camp near Shebeeley in the Hiran region north of the capital, Mogadishu.
Targets included munition storage facilities, an intelligence site and a military training camp.
The airstrike was in response to an attack against Somali forces by a "large group" of al-Shabab extremists.
In addition to U.S. and coalition strikes, Iraqi fighter aircraft have also attacked ISIS targets inside Syria recently.
In an examination of drone strikes this year alone, AP found that at least 30 of the dead likely did not belong to al-Qaida.
The announcement appeared aimed at suggesting that the Saudi government was behind the decision.
The U.S. has carried out over two dozen such airstrikes this year against the al-Qaida-linked al-Shabab.
The strike took place Thursday when the mosque was being used by ISIS to coordinate attacks on coalition forces.
The U.S. Marine Corps' F-35B made its combat debut this week, conducting its first strike in Afghanistan.
Afghan and U.S. forces resumed fighting after the Taliban chose not to extend a short cease-fire.
Maj. Gen. John Richardson IV has launched a yearlong effort to heal the base's deeply scarred image.
Congressman Dan Crenshaw is a former Navy SEAL and the headliner in one of the most hyped-up joint campaign ads ever.
You may soon be able to pick up your prescriptions at the commissary or exchange without waiting in line.
The Marine Corps is considering a plan in which it could funnel all recruits to a new base.
The mere possibility of the Marine Corps shaking up where it trains new recruits has drawn swift backlash.